Work Done by Titin Protein Folding Assists Muscle Contraction

Current theories of muscle contraction propose that the power stroke of a myosin motor is the sole source of mechanical energy driving the sliding filaments of a contracting muscle. These models exclude titin, the largest protein in the human body, which determines the passive elasticity of muscles....

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Bibliographic Details
Main Authors: Jaime Andrés Rivas-Pardo, Edward C. Eckels, Ionel Popa, Pallav Kosuri, Wolfgang A. Linke, Julio M. Fernández
Format: Article
Language:English
Published: Elsevier 2016-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716000462