Macrophage migration inhibitory factor (MIF) suppresses mitophagy through disturbing the protein interaction of PINK1-Parkin in sepsis-associated acute kidney injury

Macrophage migration inhibitory factor (MIF) suppresses mitophagy through disturbing the protein interaction of PINK1-Parkin in sepsis-associated acute kidney injury

Abstract Damage to renal tubular epithelial cells (RTECs) signaled the onset and progression of sepsis-associated acute kidney injury (SA-AKI). Recent research on mitochondria has revealed that mitophagy plays a crucial physiological role in alleviating injury to RTECs and it is suppressed progressi...

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Bibliographic Details
Main Authors: Tianlong Li, Jiachen Qu, Chang Hu, Jingjing Pang, Yaoyao Qian, Yiming Li, Zhiyong Peng
Format: Article
Language:English
Published: Nature Publishing Group 2024-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06826-z

Internet

https://doi.org/10.1038/s41419-024-06826-z

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