Skeletal contraction: A novel strategy to access multisubstituted cyclobutane

The polysubstituted and spirocyclic cyclobutanes were efficiently constructed by the utilization of a novel skeletal contraction strategy which only took one-step synthesis from the readily accessible pyrrolidines. The mechanistic studies indicated that a key intermediate N-aminated pyrrolidine was...

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Bibliographic Details
Main Authors: Chunfa Xu, V.U. Bhaskara Rao, Fen-Er Chen
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2022-02-01
Series:Green Synthesis and Catalysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666554921001101