Urine cell-free DNA multi-omics to detect MRD and predict survival in bladder cancer patients

Urine cell-free DNA multi-omics to detect MRD and predict survival in bladder cancer patients

Abstract Circulating tumor DNA (ctDNA) sensitivity remains subpar for molecular residual disease (MRD) detection in bladder cancer patients. To remedy this problem, we focused on the biofluid most proximal to the disease, urine, and analyzed urine tumor DNA in 74 localized bladder cancer patients. W...

Full description

Bibliographic Details
Main Authors: Pradeep S. Chauhan, Alexander Shiang, Irfan Alahi, R. Taylor Sundby, Wenjia Feng, Bilge Gungoren, Cayce Nawaf, Kevin Chen, Ramandeep K. Babbra, Peter K. Harris, Faridi Qaium, Casey Hatscher, Anna Antiporda, Lindsey Brunt, Lindsey R. Mayer, Jack F. Shern, Brian C. Baumann, Eric H. Kim, Melissa A. Reimers, Zachary L. Smith, Aadel A. Chaudhuri
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-022-00345-w

Internet

https://doi.org/10.1038/s41698-022-00345-w

Similar Items