Differential deregulation of NGF and BDNF neurotrophins in a transgenic rat model of Alzheimer's disease

Differential deregulation of NGF and BDNF neurotrophins in a transgenic rat model of Alzheimer's disease

Evidence from human neuropathological studies indicates that the levels of the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are compromised in Alzheimer's disease. However, the causes and temporal (pathology-dependent) evolution of these alterations are n...

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Detalles Bibliográficos
Autores principales: M. Florencia Iulita, M. Beatriz Bistué Millón, Rowan Pentz, Lisi Flores Aguilar, Sonia Do Carmo, Simon Allard, Bernadeta Michalski, Edward N. Wilson, Adriana Ducatenzeiler, Martin A. Bruno, Margaret Fahnestock, A. Claudio Cuello
Formato: Artículo
Lenguaje:English
Publicado: Elsevier 2017-12-01
Colección:Neurobiology of Disease
Materias:
Alzheimer's disease
Amyloid-β
Cholinergic
Nerve growth factor
proNGF
BDNF
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S0969996117302097

Internet

http://www.sciencedirect.com/science/article/pii/S0969996117302097

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