Aptamer-Conjugated Tb(III)-Doped Silica Nanoparticles for Luminescent Detection of Leukemia Cells

Aptamer-Conjugated Tb(III)-Doped Silica Nanoparticles for Luminescent Detection of Leukemia Cells

DNA aptamers have many benefits for cell imaging, such as high affinity and specificity, easiness of chemical functionalization, and low cost of production. Among known aptamers, Sgc8-aptamer was selected against acute lymphoblastic leukemia cells with a dissociation constant in a nanomolar range. T...

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Bibliographic Details
Main Authors: Yaroslav A. Grechkin, Svetlana L. Grechkina, Emil A. Zaripov, Svetlana V. Fedorenko, Asiya R. Mustafina, Maxim V. Berezovski
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Biomedicines
Subjects:
dna aptamers
silica nanoparticles
leukemia cells
luminescence
probes
Online Access:https://www.mdpi.com/2227-9059/8/1/14

Internet

https://www.mdpi.com/2227-9059/8/1/14

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