Enhanced biofilm and extracellular matrix production by chronic carriage versus acute isolates of Salmonella Typhi.

Salmonella Typhi is the primary causative agent of typhoid fever; an acute systemic infection that leads to chronic carriage in 3-5% of individuals. Chronic carriers are asymptomatic, difficult to treat and serve as reservoirs for typhoid outbreaks. Understanding the factors that contribute to chron...

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Bibliographic Details
Main Authors: Aishwarya Devaraj, Juan F González, Bradley Eichar, Gatan Thilliez, Robert A Kingsley, Stephen Baker, Marc W Allard, Lauren O Bakaletz, John S Gunn, Steven D Goodman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009209