Low Dose of Apelin-36 Attenuates ER Stress-Associated Apoptosis in Rats with Ischemic Stroke

Low Dose of Apelin-36 Attenuates ER Stress-Associated Apoptosis in Rats with Ischemic Stroke

Cerebral ischemia/reperfusion (I/R) injury-induced cellular apoptosis contributes to neuronal death in ischemic stroke, while endoplasmic reticulum stress (ERS) and subsequently triggered unfolded protein response (UPR) are the major mechanisms of cerebral I/R injury-induced apoptosis. A number of s...

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Bibliographic Details
Main Authors: Jian Qiu, Xin Wang, Fei Wu, Lei Wan, Baohua Cheng, Yili Wu, Bo Bai
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Neurology
Subjects:
apelin-36
ischemic stroke
apoptosis
endoplasmic reticulum stress
unfolded protein response
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00556/full

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http://journal.frontiersin.org/article/10.3389/fneur.2017.00556/full

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