Low-Dose Dose–Response for In Vitro Nrf2-ARE Activation in Human HepG2 Cells

Kelch-like ECH-associated protein 1 (Keap1), nuclear factor erythroid 2-like factor 2-related factor 2 (Nrf2), and the antioxidant response element (ARE) are interacting components of a master regulatory signaling pathway that coordinates redox homeostasis, cytoprotective responses, and shifts in st...

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Bibliographic Details
Main Author: Kenneth T. Bogen
Format: Article
Language:English
Published: SAGE Publishing 2017-04-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/1559325817699696