Sphingosine 1-phosphate in acute dengue infection.

BACKGROUND:Vascular leak is the hallmark of severe dengue infections and leads to complications such as shock and multi-organ failure. Although many mediators have been implicated in the vascular leak in dengue, the role of sphingosine 1-phosphate (S1P) has not been investigated. METHOLODOLOGY/PRINC...

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Main Authors: Laksiri Gomes, Samitha Fernando, Randika Heshan Fernando, Nilanka Wickramasinghe, Narangoda Liyanage Ajantha Shyamali, Graham S Ogg, Gathsaurie Neelika Malavige
Format: Article
Jezik:English
Izdano: Public Library of Science (PLoS) 2014-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC4237441?pdf=render