Fibroblast growth factor 21 is expressed and secreted from skeletal muscle following electrical stimulation via extracellular ATP activation of the PI3K/Akt/mTOR signaling pathway

Fibroblast growth factor 21 is expressed and secreted from skeletal muscle following electrical stimulation via extracellular ATP activation of the PI3K/Akt/mTOR signaling pathway

Fibroblast growth factor 21 (FGF21) is a hormone involved in the regulation of lipid, glucose, and energy metabolism. Although it is released mainly from the liver, in recent years it has been shown that it is a “myokine”, synthesized in skeletal muscles after exercise and stress conditions through...

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Bibliographic Details
Main Authors: Manuel Arias-Calderón, Mariana Casas, Julián Balanta-Melo, Camilo Morales-Jiménez, Nadia Hernández, Paola Llanos, Enrique Jaimovich, Sonja Buvinic
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Endocrinology
Subjects:
fibroblast growth factor 21
extracellular nucleotides
myokines
Akt signaling
excitation-transcription coupling
membrane depolarization
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1059020/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1059020/full

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