Status of Agents Targeting the HGF/c-Met Axis in Lung Cancer

Status of Agents Targeting the HGF/c-Met Axis in Lung Cancer

Hepatocyte growth factor (HGF) is the ligand for the tyrosine kinase receptor c-Met (Mesenchymal Epithelial Transition Factor also known as Hepatocyte Growth Factor Receptor, HGFR), a receptor with expression throughout epithelial and endothelial cell types. Activation of c-Met enhances cell prolife...

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Bibliographic Details
Main Authors: Oshin Miranda, Mariya Farooqui, Jill M. Siegfried
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Cancers
Subjects:
hepatocyte growth factor (HGF)
c-Met (mesenchymal epithelial transition factor or hepatocyte growth factor receptor)
targeted therapy
lung cancer
Online Access:http://www.mdpi.com/2072-6694/10/9/280

Internet

http://www.mdpi.com/2072-6694/10/9/280

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