Single‐cell profiling of transcriptomic changes during in vitro maturation of human oocytes

Single‐cell profiling of transcriptomic changes during in vitro maturation of human oocytes

Abstract Purpose In vitro maturation (IVM) of human oocytes offers an invaluable opportunity for infertility treatment. However, in vitro matured oocytes often show lower developmental abilities than their in vivo counterparts, and molecular mechanisms underlying successful maturation remain unclear...

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Bibliographic Details
Main Authors: Hiroki Takeuchi, Mari Yamamoto, Megumi Fukui, Akihiro Inoue, Tadashi Maezawa, Mikiko Nishioka, Eiji Kondo, Tomoaki Ikeda, Kazuya Matsumoto, Kei Miyamoto
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Reproductive Medicine and Biology
Subjects:
delay in oocyte maturation
human oocyte
oocyte maturation
single‐cell RNA‐sequencing
transcriptome
Online Access:https://doi.org/10.1002/rmb2.12464

Internet

https://doi.org/10.1002/rmb2.12464

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