Increased Methyl-CpG-Binding Domain Protein 2 Promotes Cigarette Smoke-Induced Pulmonary Hypertension

Increased Methyl-CpG-Binding Domain Protein 2 Promotes Cigarette Smoke-Induced Pulmonary Hypertension

Pulmonary hypertension (PH) is a chronic vascular proliferative disorder. While cigarette smoke (CS) plays a vital part in PH related to chronic obstructive pulmonary disease (COPD). Methyl-CpG-Binding Domain Protein 2 (MBD2) has been linked to multiple proliferative diseases. However, the specific...

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Bibliographic Details
Main Authors: Jixing Wu, Qian Huang, Qinghai Li, Yiya Gu, Yuan Zhan, Ting Wang, Jinkun Chen, Zhilin Zeng, Yongman Lv, Jianping Zhao, Jie Xia, Jungang Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
pulmonary hypertension
MBD2
cigarette smoke
pulmonary artery smooth muscle cells
BMP2
pulmonary vascular remodeling
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.879793/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.879793/full

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