Feasibility and application of machine learning enabled fast screening of poly-beta-amino-esters for cartilage therapies

Abstract Despite the large prevalence of diseases affecting cartilage (e.g. knee osteoarthritis affecting 16% of population globally), no curative treatments are available because of the limited capacity of drugs to localise in such tissue caused by low vascularisation and electrostatic repulsion. W...

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Bibliographic Details
Main Authors: Stefano Perni, Polina Prokopovich
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-18332-3