Sumoylation-deficient phosphoglycerate mutase 2 impairs myogenic differentiation

Sumoylation-deficient phosphoglycerate mutase 2 impairs myogenic differentiation

Phosphoglycerate mutase 2 (PGAM2) is a critical glycolytic enzyme that is highly expressed in skeletal muscle. In humans, naturally occurring mutations in Phosphoglycerate mutase 2 have been etiologically linked to glycogen storage disease X (GSDX). Phosphoglycerate mutase 2 activity is regulated by...

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Bibliographic Details
Main Authors: Yi Zhang, Ilimbek Beketaev, Yanlin Ma, Jun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
phosphoglycerate mutase 2
sumoylation
posttranslational modification
myogenic differentiation
mitochondrial function
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1052363/full

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https://www.frontiersin.org/articles/10.3389/fcell.2022.1052363/full

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