Ginseng Extracts, GS-KG9 and GS-E3D, Prevent Blood–Brain Barrier Disruption and Thereby Inhibit Apoptotic Cell Death of Hippocampal Neurons in Streptozotocin-Induced Diabetic Rats

Ginseng Extracts, GS-KG9 and GS-E3D, Prevent Blood–Brain Barrier Disruption and Thereby Inhibit Apoptotic Cell Death of Hippocampal Neurons in Streptozotocin-Induced Diabetic Rats

Type 1 diabetes mellitus is known to be linked to the impairment of blood–brain barrier (BBB) integrity following neuronal cell death. Here, we investigated whether GS-KG9 and GS-E3D, bioactive ginseng extracts from Korean ginseng (<i>Panax ginseng</i> Meyer), inhibit BBB disruption foll...

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Bibliographic Details
Main Authors: Jee Youn Lee, Chan Sol Park, Hae Young Choi, Sung Hyun Chung, Mi Kyung Pyo, Tae Young Yune
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Nutrients
Subjects:
blood–brain barrier
apoptosis
hippocampus
microglia
astrocyte
streptozotocin
Online Access:https://www.mdpi.com/2072-6643/12/8/2383

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https://www.mdpi.com/2072-6643/12/8/2383

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