Quantitative analysis of macroscopic solute transport in the murine brain

Abstract Background Understanding molecular transport in the brain is critical to care and prevention of neurological disease and injury. A key question is whether transport occurs primarily by diffusion, or also by convection or dispersion. Dynamic contrast-enhanced (DCE-MRI) experiments have long...

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Bibliographic Details
Main Authors: Lori A. Ray, Martin Pike, Matthew Simon, Jeffrey J. Iliff, Jeffrey J. Heys
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:https://doi.org/10.1186/s12987-021-00290-z