Mutations in the DI-DII Linker of Human Parainfluenza Virus Type 3 Fusion Protein Result in Diminished Fusion Activity.

Mutations in the DI-DII Linker of Human Parainfluenza Virus Type 3 Fusion Protein Result in Diminished Fusion Activity.

Human parainfluenza virus type 3 (HPIV3) can cause severe respiratory tract diseases in infants and young children, but no licensed vaccines or antiviral agents are currently available for treatment. Fusing the viral and target cell membranes is a prerequisite for its entry into host cells and is di...

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Bibliographic Details
Main Authors: Wenyan Xie, Hongling Wen, Fulu Chu, Shaofeng Yan, Bin Lin, Wenli Xie, Ying Liu, Guijie Ren, Li Zhao, Yanyan Song, Chengxi Sun, Zhiyu Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4549179?pdf=render

Internet

http://europepmc.org/articles/PMC4549179?pdf=render

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