Thioctamer: a novel thioctic acid–glatiramer acetate nanoconjugate expedites wound healing in diabetic rats

Thioctamer: a novel thioctic acid–glatiramer acetate nanoconjugate expedites wound healing in diabetic rats

AbstractThe current work aims to design thioctic acid (TA) and glatiramer acetate (GA) nanoconjugate (thioctamer) loaded hydrogel formula as well as evaluation of thioctamer preclinical efficacy in expediting wound healing in a rat model of the diabetic wound. Thioctamer was prepared by conjugation...

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Bibliographic Details
Main Authors: Nabil A. Alhakamy, Gamal A. Mohamed, Usama A. Fahmy, Basma G. Eid, Mohammed W. Al-Rabia, Amgad I. M. Khedr, Mohammed Z. Nasrullah, Sabrin R. M. Ibrahim, Ashraf B. Abdel-Naim, Osama A. A. Ahmed, Shadab Md
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Drug Delivery
Subjects:
Alpha-lipoic acid
diabetic wounds
nanoparticles
HPMC hydrogel
TNF-α
IL-6
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2022.2081382

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https://www.tandfonline.com/doi/10.1080/10717544.2022.2081382

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