MRPS36 provides a structural link in the eukaryotic 2-oxoglutarate dehydrogenase complex

MRPS36 provides a structural link in the eukaryotic 2-oxoglutarate dehydrogenase complex

The tricarboxylic acid cycle is the central pathway of energy production in eukaryotic cells and plays a key part in aerobic respiration throughout all kingdoms of life. One of the pivotal enzymes in this cycle is 2-oxoglutarate dehydrogenase complex (OGDHC), which generates NADH by oxidative decarb...

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Bibliographic Details
Main Authors: Johannes F. Hevler, Pascal Albanese, Alfredo Cabrera-Orefice, Alisa Potter, Andris Jankevics, Jelena Misic, Richard A. Scheltema, Ulrich Brandt, Susanne Arnold, Albert J. R. Heck
Format: Article
Language:English
Published: The Royal Society 2023-03-01
Series:Open Biology
Subjects:
2-oxoglutarate dehydrogenase (OGDHC)
MRPS36
tricarboxylic acid (TCA) cycle
cross-linking mass spectrometry
complexome profiling
structural biology
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.220363

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https://royalsocietypublishing.org/doi/10.1098/rsob.220363

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