Functional cooperation between ATG7/autophagy and the PALB2 tumor suppressor in mitochondrial regulation, redox homeostasis, and neuronal health

In a recently published study, we described a genetic interaction and functional cooperation between Atg7, an essential autophagy gene, and Palb2, a breast cancer susceptibility gene, in the maintenance of mitochondrial function, redox homeostasis, and neuronal viability. Our studies uncovered a new...

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Bibliographic Details
Main Authors: Yanying Huo, Akshada Sawant, Eileen White, Bing Xia
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Autophagy Reports
Online Access:http://dx.doi.org/10.1080/27694127.2022.2080314