Three-dimensional characterization of developing and adult ocular vasculature in mice using in toto clearing
An organic-solvent based clearing technique is used to visualize the vasculature in 3D using light sheet microscopy in retinal and hyaloid vessel development, and applied to branch retinal vein occlusion (BRVO) models.
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-10-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-022-04104-2 |