Enhanced therapeutic effects of apoptotic cell‐conditioned mesenchymal stem cells in lupus‐prone MRL/lpr mice

Enhanced therapeutic effects of apoptotic cell‐conditioned mesenchymal stem cells in lupus‐prone MRL/lpr mice

Abstract Background Apoptotic cell‐conditioned mesenchymal stem cells (AC‐MSCs) exhibit stronger T cell suppressive ability via cyclooxygenase 2 (COX2)/prostaglandin E2 (PGE2); however, whether AC‐MSCs exhibit enhanced therapeutic effects on systemic lupus erythematosus (SLE) remains unknown. Method...

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Bibliographic Details
Main Authors: Zhuoya Zhang, Yiyuan Cui, Saisai Huang, Weilin Liu, Chen Chen, Xuebing Feng, Dandan Wang, Lingyun Sun
Format: Article
Language:English
Published: Wiley 2024-06-01
Series:Rheumatology & Autoimmunity
Subjects:
apoptotic cells
mesenchymal stem cells
precondition
prostaglandin E2
systemic lupus erythematosus
Online Access:https://doi.org/10.1002/rai2.12122

Internet

https://doi.org/10.1002/rai2.12122

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