Aging-associated dysfunction of Akt/protein kinase B: S-nitrosylation and acetaminophen intervention.

BACKGROUND:Aged skeletal muscle is characterized by an increased incidence of metabolic and functional disorders, which if allowed to proceed unchecked can lead to increased morbidity and mortality. The mechanism(s) underlying the development of these disorders in aging skeletal muscle are not well...

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Main Authors: Miaozong Wu, Anjaiah Katta, Murali K Gadde, Hua Liu, Sunil K Kakarla, Jacqueline Fannin, Satyanarayana Paturi, Ravi K Arvapalli, Kevin M Rice, Yeling Wang, Eric R Blough
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2712760?pdf=render