DNA Aptamers against Taiwan Banded Krait α-Bungarotoxin Recognize Taiwan Cobra Cardiotoxins

Bungarus multicinctus α-bungarotoxin (α-Bgt) and Naja atra cardiotoxins (CTXs) share a common structural scaffold, and their tertiary structures adopt three-fingered loop motifs. Four DNA aptamers against α-Bgt have been reported previously. Given that the binding of aptamers with targeted proteins...

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Bibliographic Details
Main Authors: Ying-Jung Chen, Chia-Yu Tsai, Wan-Ping Hu, Long-Sen Chang
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/8/3/66