Electron paramagnetic resonance highlights that the oxygen effect contributes to the radiosensitizing effect of paclitaxel.

BACKGROUND: Paclitaxel (PTX) is a potent anti-cancer chemotherapeutic agent and is widely used in the treatments of solid tumors, particularly of the breast and ovaries. An effective and safe micellar formulation of PTX was used to administer higher doses of PTX than Taxol® (the current commercializ...

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Bibliographic Details
Main Authors: Fabienne Danhier, Pierre Danhier, Nicolas Magotteaux, Géraldine De Preter, Bernard Ucakar, Oussama Karroum, Bénédicte Jordan, Bernard Gallez, Véronique Préat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3395636?pdf=render