Semen inhibits Zika virus infection of cells and tissues from the anogenital region

Semen inhibits Zika virus infection of cells and tissues from the anogenital region

Semen from Zika virus infected individuals can contain high viral loads and can result in sexual transmission. Here, Müller et al. show that semen, and particularly seminal preparations containing extracellular vesicles, inhibit infection of Zika and other flaviviruses.

Bibliographic Details
Main Authors: Janis A. Müller, Mirja Harms, Franziska Krüger, Rüdiger Groß, Simone Joas, Manuel Hayn, Andrea N. Dietz, Sina Lippold, Jens von Einem, Axel Schubert, Manuela Michel, Benjamin Mayer, Mirko Cortese, Karen S. Jang, Nathallie Sandi-Monroy, Miriam Deniz, Florian Ebner, Olli Vapalahti, Markus Otto, Ralf Bartenschlager, Jean-Philippe Herbeuval, Jonas Schmidt-Chanasit, Nadia R. Roan, Jan Münch
Format: Article
Language:English
Published: Nature Portfolio 2018-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-04442-y

Internet

https://doi.org/10.1038/s41467-018-04442-y

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