Differential regulation of TNFα and IL-6 expression contributes to immune evasion in prostate cancer

Differential regulation of TNFα and IL-6 expression contributes to immune evasion in prostate cancer

Abstract Background The role of the inflammatory milieu in prostate cancer progression is not well understood. Differences in inflammatory signaling between localized and metastatic disease may point to opportunities for early intervention. Methods We modeled PCa disease progression by analyzing RNA...

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Bibliographic Details
Main Authors: Ida Deichaite, Timothy J. Sears, Leisa Sutton, Daniel Rebibo, Kylie Morgan, Tyler Nelson, Brent Rose, Pablo Tamayo, Napoleone Ferrara, Fotis Asimakopoulos, Hannah Carter
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Journal of Translational Medicine
Subjects:
Prostate cancer
TNF
IL-6
ADAMTS-4
AP-1
FOSB
Online Access:https://doi.org/10.1186/s12967-022-03731-x

Internet

https://doi.org/10.1186/s12967-022-03731-x

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