A Vimentin-Targeting Oral Compound with Host-Directed Antiviral and Anti-Inflammatory Actions Addresses Multiple Features of COVID-19 and Related Diseases

A Vimentin-Targeting Oral Compound with Host-Directed Antiviral and Anti-Inflammatory Actions Addresses Multiple Features of COVID-19 and Related Diseases

With the Delta variant currently fueling a resurgence of new infections in the fully vaccinated population, developing an effective therapeutic drug is especially critical and urgent in fighting COVID-19. In contrast to the many efforts to repurpose existing drugs or address only one aspect of COVID...

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Bibliographic Details
Main Authors: Zhizhen Li, Jianping Wu, Ji Zhou, Baoshi Yuan, Jiqiao Chen, Wanchen Wu, Lian Mo, Zhipeng Qu, Fei Zhou, Yingying Dong, Kai Huang, Zhiwei Liu, Tao Wang, Deebie Symmes, Jingliang Gu, Eiketsu Sho, Jingping Zhang, Ruihuan Chen, Ying Xu
Format: Article
Language:English
Published: American Society for Microbiology 2021-10-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.02542-21

Internet

https://journals.asm.org/doi/10.1128/mBio.02542-21

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