TangShenWeiNing Formula Prevents Diabetic Nephropathy by Protecting Podocytes Through the SIRT1/HIF-1α Pathway

TangShenWeiNing Formula Prevents Diabetic Nephropathy by Protecting Podocytes Through the SIRT1/HIF-1α Pathway

BackgroundDiabetic nephropathy (DN) represents a major complication of diabetes, and podocyte injury has a critical function in DN development. TangShenWeiNing formula (TSWN) has been demonstrated to efficiently decrease proteinuria and protect podocytes in DN. This work aimed to explore the mechani...

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Bibliographic Details
Main Authors: Jing Chang, Jinsu Zheng, Xia Gao, Hengbei Dong, Haitian Yu, Mengxiu Huang, Zhencheng Sun, Xiaomeng Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Endocrinology
Subjects:
TangShenWeiNing formula
diabetic nephropathy
podocytes (MeSH: D050199)
SIRT1
HIF-1α
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.888611/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.888611/full

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