Transforming growth factor-ß as a therapeutic target for the cardiac damage of Chagas disease

Transforming growth factor beta (TGF-β) is deeply involved on the pathogenesis of Chagas disease. Our group has been investigating the participation of this pleiotropic cytokine in different aspects of Chagas disease over the last 20 years. Important observations have been made, such as: (i) the abi...

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Main Authors: Mariana Caldas Waghabi, Roberto Rodrigues Ferreira, Rayane da Silva Abreu, Wim Degrave, Elen Mello de Souza, Sabine Bailly, Jean-Jacques Feige, Tania C de Araújo-Jorge
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2022-02-01
Series:Memorias do Instituto Oswaldo Cruz
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762022000100851&tlng=en