High-concentration sevoflurane exposure in mid-gestation induces apoptosis of neural stem cells in rat offspring

High-concentration sevoflurane exposure in mid-gestation induces apoptosis of neural stem cells in rat offspring

Sevoflurane is the most commonly used volatile anesthetic during pregnancy. The viability of neural stem cells directly affects the development of the brain. However, it is unknown whether the use of sevoflurane during the second trimester affects the survival of fetal neural stem cells. Therefore,...

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Bibliographic Details
Main Authors: Yuan Wang, Shao-Wei Yin, Nan Zhang, Ping Zhao
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; sevoflurane; neural stem cells; apoptosis; vascular endothelial growth factor; PI3K; p-AKT; anesthesia; learning; memory; developmental neurobiology; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=9;spage=1575;epage=1584;aulast=Wang

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=9;spage=1575;epage=1584;aulast=Wang

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