Bile acids. LI. Formation of 12α-hydroxyl derivatives and companions from 5α-sterols by rabbit liver microsomes

A comparison of the activity of rabbit liver microsomes fortified with 0.1 mM NADPH to promote 12α-hydroxylation over 60 minutes with appropriate sterols provided the following relative order of activities: 5α-cholestane-3α, 7α-diol, 100; 7α-hydroxy-5α-cholestane-3-one, 76; 7α-hydroxycholest-4-en-3-...

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Bibliographic Details
Main Authors: S S Ali, W H Elliott
Format: Article
Language:English
Published: Elsevier 1976-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520349233