The RNA Demethylase ALKBH5 Maintains Endoplasmic Reticulum Homeostasis by Regulating UPR, Autophagy, and Mitochondrial Function

The RNA Demethylase ALKBH5 Maintains Endoplasmic Reticulum Homeostasis by Regulating UPR, Autophagy, and Mitochondrial Function

Eukaryotic cells maintain cellular fitness by employing well-coordinated and evolutionarily conserved processes that negotiate stress induced by internal or external environments. These processes include the unfolded protein response, autophagy, endoplasmic reticulum-associated degradation (ERAD) of...

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Bibliographic Details
Main Authors: Panneerdoss Subbarayalu, Pooja Yadav, Santosh Timilsina, Daisy Medina, Kunal Baxi, Robert Hromas, Ratna K. Vadlamudi, Yidong Chen, Patrick Sung, Manjeet K. Rao
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
ALKBH5
m6A
unfolded protein response
mitochondria
ERLIN1
ER homeostasis
Online Access:https://www.mdpi.com/2073-4409/12/9/1283

Internet

https://www.mdpi.com/2073-4409/12/9/1283

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