Mitochondrial DNA: Distribution, Mutations, and Elimination

Mitochondrion harbors its own DNA (mtDNA), which encodes many critical proteins for the assembly and activity of mitochondrial respiratory complexes. mtDNA is packed by many proteins to form a nucleoid that uniformly distributes within the mitochondrial matrix, which is essential for mitochondrial f...

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Bibliographic Details
Main Authors: Chaojun Yan, Xiaoying Duanmu, Ling Zeng, Bing Liu, Zhiyin Song
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/4/379