Novel goose parvovirus VP1 targets IRF7 protein to block the type I interferon upstream signaling pathway

Novel goose parvovirus VP1 targets IRF7 protein to block the type I interferon upstream signaling pathway

ABSTRACT: Outbreaks of short beak and dwarfism syndrome (SBDS), caused by a novel goose parvovirus (NGPV), have occurred in China since 2015. The NGPV, a single-stranded DNA virus, is thought to be vertically transmitted. However, the mechanism of NGPV immune evasion remains unclear. In this study,...

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Bibliographic Details
Main Authors: You-tian Yang, Zhi-chao Deng, Liu-jun Zhang, Xin-liang Fu, Chen Fu, Xiao-zhi Zhan, Yun-bo Tian, Wen-jun Liu
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Poultry Science
Subjects:
NGPV
IFN
cGAS-STING
IRF-7
immune evasion
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579124006448

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http://www.sciencedirect.com/science/article/pii/S0032579124006448

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