Relevance of different prior knowledge sources for inferring gene interaction networks

Relevance of different prior knowledge sources for inferring gene interaction networks

When inferring networks from high-throughput genomic data, one of the main challenges is the subsequent validation of these networks. In the best case scenario, the true network is partially known from previous research results published in structured databases or research articles. Traditionally, i...

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Bibliographic Details
Main Authors: Catharina eOlsen, Gianluca eBontempi, Frank eEmmert-Streib, John eQuackenbush, Benjamin eHaibe-Kains
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Genetics
Subjects:
Colon Cancer
Validation
Network Inference
knockdown
Prior Knowledge
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00177/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00177/full

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