Senescence marker protein 30 has a cardio-protective role in doxorubicin-induced cardiac dysfunction.

BACKGROUND: Senescence marker protein 30 (SMP30), which was originally identified as an aging marker protein, is assumed to act as a novel anti-aging factor in the liver, lungs and brain. We hypothesized that SMP30 has cardio-protective function due to its anti-aging and anti-oxidant effects on doxo...

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Bibliographic Details
Main Authors: Makiko Miyata, Satoshi Suzuki, Tomofumi Misaka, Tetsuro Shishido, Shu-Ichi Saitoh, Akihito Ishigami, Isao Kubota, Yasuchika Takeishi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3876969?pdf=render