Investigating the Role of the microRNA-34/449 Family in Male Infertility: A Critical Analysis and Review of the Literature

Investigating the Role of the microRNA-34/449 Family in Male Infertility: A Critical Analysis and Review of the Literature

There is a great body of evidence suggesting that in both humans and animal models the microRNA-34/449 (miR-34/449) family plays a crucial role for normal testicular functionality as well as for successful spermatogenesis, regulating spermatozoa maturation and functionality. This review and critical...

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Bibliographic Details
Main Authors: Konstantinos Pantos, Sokratis Grigoriadis, Penelope Tomara, Ioanna Louka, Evangelos Maziotis, Agni Pantou, Nikolaos Nitsos, Terpsithea Vaxevanoglou, Georgia Kokkali, Ashok Agarwal, Konstantinos Sfakianoudis, Mara Simopoulou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Endocrinology
Subjects:
male infertility
idiopathic male infertility
micro-ribonucleic acids (microRNAs)
miR-34/449
spermatogenesis
ciliogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.709943/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.709943/full

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