Use of Multiplex Quantitative PCR To Evaluate the Impact of Pneumococcal Conjugate Vaccine on Nasopharyngeal Pneumococcal Colonization in African Children

Use of Multiplex Quantitative PCR To Evaluate the Impact of Pneumococcal Conjugate Vaccine on Nasopharyngeal Pneumococcal Colonization in African Children

ABSTRACT Pneumococcal conjugate vaccine (PCV) immunization of children induces shifts in colonizing pneumococcal serotypes. This study evaluated the effect of infant vaccination with 7-valent PCV (PCV7) on vaccine serotype (VT) colonization and whether the increase in nonvaccine serotype (NVT) was d...

Full description

Bibliographic Details
Main Authors: Courtney P. Olwagen, Peter V. Adrian, Marta C. Nunes, Michelle J. Groome, Mark F. Cotton, Avy Violari, Shabir A. Madhi
Format: Article
Language:English
Published: American Society for Microbiology 2017-12-01
Series:mSphere
Subjects:
PCV7 vaccination
serotype replacement
unmasking
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00404-17

Internet

https://journals.asm.org/doi/10.1128/mSphere.00404-17

Similar Items