SP-1, a Serine Protease from the Gut Microbiota, Influences Colitis and Drives Intestinal Dysbiosis in Mice

SP-1, a Serine Protease from the Gut Microbiota, Influences Colitis and Drives Intestinal Dysbiosis in Mice

Increased protease activity has been linked to the pathogenesis of IBD. While most studies have been focusing on host proteases in gut inflammation, it remains unclear how to address the potential contribution of their bacterial counterparts. In the present study, we report a functional characteriza...

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Bibliographic Details
Main Authors: Aicha Kriaa, Amin Jablaoui, Soufien Rhimi, Souha Soussou, Héla Mkaouar, Vincent Mariaule, Natalia Gruba, Ali Gargouri, Emmanuelle Maguin, Adam Lesner, Moez Rhimi
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
inflammatory bowel diseases
gut microbiota
serine proteases
microbiome
holobiont
Online Access:https://www.mdpi.com/2073-4409/10/10/2658

Internet

https://www.mdpi.com/2073-4409/10/10/2658

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