MACSE: Multiple Alignment of Coding SEquences accounting for frameshifts and stop codons.

Until now the most efficient solution to align nucleotide sequences containing open reading frames was to use indirect procedures that align amino acid translation before reporting the inferred gap positions at the codon level. There are two important pitfalls with this approach. Firstly, any premat...

Full description

Bibliographic Details
Main Authors: Vincent Ranwez, Sébastien Harispe, Frédéric Delsuc, Emmanuel J P Douzery
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21949676/pdf/?tool=EBI