Increased infectivity in human cells and resistance to antibody-mediated neutralization by truncation of the SIV gp41 cytoplasmic tail

The role of antibodies in protecting the host from human immunodeficiency virus type 1 (HIV-1) infection is of considerable interest, particularly because the RV144 trial results suggest that antibodies contribute to protection. Although infection of nonhuman primates with simian immunodeficiency vi...

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Bibliographic Details
Main Authors: Takeo eKuwata, Kaori eTakaki, Ikumi eEnomoto, Kazuhisa eYoshimura, Shuzo eMatsushita
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00117/full