Biophysical chemistry behind sickle cell anemia and the mechanism of voxelotor action

Abstract Sickle cell anemia disease has been a great challenge to the world in the present situation. It occurs only due to the polymerization of sickle hemoglobin (HbS) having Pro–Val–Glu typed mutation, while the polymerization does not occur in normal hemoglobin (HbA) having Pro–Glu–Glu peptides....

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолч: Mohd. Suhail
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Nature Portfolio 2024-01-01
Цуврал:Scientific Reports
Онлайн хандалт:https://doi.org/10.1038/s41598-024-52476-8