Distinct roles for type I and type III interferons in virulent human metapneumovirus pathogenesis.

Human metapneumovirus (HMPV) is an important cause of acute lower respiratory infection in children and adults worldwide. There are four genetic subgroups of HMPV and both neutralizing antibodies and T cells contribute to protection. However, little is known about mechanisms of pathogenesis and most...

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Bibliographic Details
Main Authors: Yu Zhang, Jiuyang Xu, Margot Miranda-Katz, Jorna Sojati, Sharon J Tollefson, Michelle L Manni, John F Alcorn, Saumendra N Sarkar, John V Williams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-02-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011840&type=printable