PER-TIM interactions with the photoreceptor cryptochrome mediate circadian temperature responses in Drosophila.
Drosophila cryptochrome (CRY) is a key circadian photoreceptor that interacts with the period and timeless proteins (PER and TIM) in a light-dependent manner. We show here that a heat pulse also mediates this interaction, and heat-induced phase shifts are severely reduced in the cryptochrome loss-of...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-06-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC1877818?pdf=render |