The multifaceted role of the SASP in atherosclerosis: from mechanisms to therapeutic opportunities

Abstract Background The global population of older individuals is growing, and ageing is a key risk factor for atherosclerotic cardiovascular diseases. Abnormal accumulation of senescent cells can cause potentially deleterious effects on the organism with age. As a vital marker of cellular senescenc...

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Bibliographic Details
Main Authors: Yu Sun, Xia Wang, Tianwei Liu, Xiaoyan Zhu, Xudong Pan
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-022-00815-5