Custom design and analysis of high-density oligonucleotide bacterial tiling microarrays.

BACKGROUND: High-density tiling microarrays are a powerful tool for the characterization of complete genomes. The two major computational challenges associated with custom-made arrays are design and analysis. Firstly, several genome dependent variables, such as the genome's complexity and seque...

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Bibliographic Details
Main Authors: Gard O S Thomassen, Alexander D Rowe, Karin Lagesen, Jessica M Lindvall, Torbjørn Rognes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2691959?pdf=render