Channel-Forming Bacterial Toxins in Biosensing and Macromolecule Delivery

Channel-Forming Bacterial Toxins in Biosensing and Macromolecule Delivery

To intoxicate cells, pore-forming bacterial toxins are evolved to allow for the transmembrane traffic of different substrates, ranging from small inorganic ions to cell-specific polypeptides. Recent developments in single-channel electrical recordings, X-ray crystallography, protein engineering, a...

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Bibliographic Details
Main Authors: Philip A. Gurnev, Ekaterina M. Nestorovich
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Toxins
Subjects:
gramicidin A
α-hemolysin
anthrax toxin
biosensing
stochastic sensing
ion channel
biological nanopore
protein translocation
targeted toxins
drug delivery
polymer transport
Online Access:http://www.mdpi.com/2072-6651/6/8/2483

Internet

http://www.mdpi.com/2072-6651/6/8/2483

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